Manager
Enzo Maresca
Manchester City travel to Old Trafford for the derby unbeaten through three rounds (wins over Bournemouth, Crystal Palace and Coventry), with Enzo Maresca's midfield still settling around his big-money summer arrival. Enzo Fernández, declared "ready" by Maresca and given his full debut in the GW3 win over Coventry, keeps the pivot spot he took over from the still-absent Nico O'Reilly (back injury, now missing three straight matchweeks). Matheus Nunes is fit and available again after his own spell out, but has yet to force his way back into the actual XI, so Khusanov is kept in at right-back on current form. Jeremy Doku remains sidelined with the calf problem picked up before the season. Nathan Ndiaye, who came in for Foden in GW3, is backed to keep his place on the right of the front three.